Spermidine, discovered in human semen in 1678, is a polyamine found rich in wheat germ, green peas, cauliflower, broccoli, mushrooms, matured cheese, soybean, natto etc. Spermidine is a longevity agent in mammals. It induces “autophagy”, the body's natural repair and recycling process of cells which involves the removal of damaged proteins and organelles from cells, thus inhibiting the aging process[1][2][3][4]. There is no coincidence that people in the regions of Sardinia (Italy), Nicoya (Costa Rica) and Loma Linda (United States), have the highest concentration of centenarians in the world. Inhabitants of these regions consume diets rich in spermidine on a daily basis. It also plays an essential role in inflammation reduction, lipid metabolism, development of immune system, and regulation of cell growth, proliferation and death[5][6].
TOP BLOSSOM SPERMIDINE RICH Wheat germ is selected from the Australian fresh wheat grains which have the highest Spermidine content. The cleaning, milling, separation and purification process is carefully controlled to produce the best quality SPERMIDINE RICH Wheat germ in the market. It is super nutritious and healthy with a delightful nutty flavour.
Serving Suggestion:
Add 2 tablespoons (30g) a day or:
- Add to cooked cereals, stews and casseroles
- Add to juices, milks, smoothes and yoghurt
- Add to baking such as bread and nut bars
Storage:
Store in a refrigerator.
References:
1. Handa AK, Fatima T, Mattoo AK. Polyamines: bio-molecules with diverse functions in plant and human health and disease. Front Chem. (2018) 6:10. doi: 10.3389/fchem.2018.00010
2. Eisenberg T, Knauer H, Schauer A, Buttner S, Ruckenstuhl C, Carmona-Gutierrez D, et al. Induction of autophagy by spermidine promotes longevity. Nat Cell Biol. (2009) 11:1305–14. doi: 10.1038/ncb1975
3. Kiechl S, Pechlaner R, Willeit P, Notdurfter M, Paulweber B, Willeit K, et al. Higher spermidine intake is linked to lower mortality: a prospective population-based study. Am J Clin Nutr. (2018) 108:371–80. doi: 10.1093/ajcn/nqy102
4. Soda K. Spermine and gene methylation: a mechanism of lifespan extension induced by polyamine-rich diet. Amino Acids. (2019). doi: 10.1007/s00726-019-02733-2. [Epub ahead of print].
5. Minois, Nadège (28 January 2014). "Molecular Basis of the "Anti-Aging" Effect of Spermidine and Other Natural Polyamines – A Mini-Review". Gerontology. 60 (4): 319–326. doi:10.1159/000356748
6. Madeo F, Eisenberg T, Pietrocola F, Kroemer G (2018). "Spermidine in health and disease". Science. 359 (6374): eaan2788. doi:10.1126/science.aan2788